Grape skin components may be turned into new anti-ageing medicines

11 Mar 2013, 17:39
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Grape skin components may be turned into new anti-ageing medicines

Among many drugs researched by scientists to extend the human life span, there are resveratrol-based substances that are being claimed to posses anti-ageing effects, and which, if applied as concentrated products, are able to help humans live longer.


The pharmaceutical giant GSK has already started testing artificial versions of synthesized resveratrol in order to study possible effects of its long-term use.


Only people with specific medical conditions take part in the studies, namely grave skin disease psoriasis and type 2 diabetes.


Organic chemical resveratrol that can be found in red wine, grape skin and some other foods is believed to have anti-ageing properties due to its ability to boost protein SIRT1 activity.


David Sinclair, professor of genetics at Harvard University, said ageing might not actually be an "irreversible affliction".


He said: "We're finding that ageing isn't the irreversible affliction that we thought it was. Some of us could live to 150, but we won't get there without more research. Things there are also looking promising. Now we are looking at whether there are benefits for those who are already healthy”.


Mice, flies and bees, when given the compounds boosting SIRT1 in similar laboratory experiments, lived longer. The body cells become less sluggish with increasing SIRT1 activity, which makes their operation much more efficient.


Professor Sinclair says he has accomplished the experiments that show these resveratrol-based chemicals having a profound effects on health. Critically oriented scientists describe the results as experimental artifice doubting their true value.


Despite the mixed reports, there is evidence of successful results in the trials of resveratrol with implications for heart failure and cardiovascular disease, cancer, Alzheimer's, Type II diabetes, muscle wasting, Parkinson's, cataracts, fatty liver disease, sleep disorders, osteoporosis and inflammatory conditions such as arthritis, colitis, and psoriasis.


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